diff --git a/CHANGELOG.md b/CHANGELOG.md
index a9e708fddb..ffd75a5626 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,6 +6,14 @@
 > make sure you follow our [migration guide](https://docs.sentry.io/platforms/react-native/migration/) first.
 <!-- prettier-ignore-end -->
 
+## Unreleased
+
+### Fixes
+
+- Make the `RNSentry` SPEC CHECKSUM in `Podfile.lock` machine-independent ([#6474](https://github.com/getsentry/sentry-react-native/pull/6474))
+
+  The prebuilt `Sentry.xcframework` is now referenced through a `$(PODS_ROOT)/sentry-xcframeworks/…` symlink instead of the absolute per-user cache path, so `Podfile.lock` no longer churns between developers and CI. Expect a one-time `RNSentry` checksum change on the next `pod install`; the `SENTRY_XCFRAMEWORK_CACHE_DIR=/tmp/…` workaround is no longer needed.
+
 ## 8.19.0
 
 ### Features
diff --git a/packages/core/RNSentry.podspec b/packages/core/RNSentry.podspec
index 0b6ee4e414..7285b21721 100644
--- a/packages/core/RNSentry.podspec
+++ b/packages/core/RNSentry.podspec
@@ -122,16 +122,24 @@ Pod::Spec.new do |s|
     # sentry-cocoa's `Sentry.xcframework` layout is stable across releases.
     # Add a slice there if a future release ships one.
     #
-    # Point the search paths at the pod-install-time absolute path to the
-    # xcframework. `${PODS_TARGET_SRCROOT}` is only defined in per-pod
-    # xcconfigs, not in aggregate/user-target xcconfigs, and a
-    # `${PODS_ROOT}`-relative fallback works for one Podfile layout but
-    # breaks for another (e.g. the RN sample apps put node_modules at a
-    # different depth from RNSentryCocoaTester). Using the absolute path
-    # avoids the layout-detection dance — the path is regenerated on
-    # every `pod install`, so it's not something anyone commits.
+    # Reference the xcframework through a `Pods/sentry-xcframeworks/…`
+    # symlink so the search paths are machine-independent (see
+    # `stage_sentry_xcframework_in_pods`) — the values below feed the
+    # `RNSentry` SPEC CHECKSUM in `Podfile.lock`, so an absolute
+    # `~/Library/Caches/…` path here made the lockfile churn between
+    # machines (#6467). `${PODS_TARGET_SRCROOT}` can't be used instead: it
+    # is only defined in per-pod xcconfigs, not in aggregate/user-target
+    # xcconfigs, and a `${PODS_ROOT}`-relative path to node_modules works
+    # for one Podfile layout but breaks for another (e.g. the RN sample
+    # apps put node_modules at a different depth from RNSentryCocoaTester).
+    # If the symlink can't be created, fall back to the absolute
+    # pod-install-time path — functional, but with a machine-specific
+    # checksum.
+    sentry_xcframework_ref =
+      stage_sentry_xcframework_in_pods(sentry_xcframework_dir, sentry_cocoa_version, 'Sentry') ||
+      sentry_xcframework_dir
     xcframework_search_paths = SENTRY_XCFRAMEWORK_SLICES_BY_SDK.each_with_object({}) do |(sdk, slice_ids), acc|
-      paths = slice_ids.map { |slice| %("#{File.join(sentry_xcframework_dir, slice)}") }
+      paths = slice_ids.map { |slice| %("#{File.join(sentry_xcframework_ref, slice)}") }
       acc["FRAMEWORK_SEARCH_PATHS[sdk=#{sdk}*]"] = (['$(inherited)'] + paths).join(' ')
     end
 
diff --git a/packages/core/scripts/sentry_utils.rb b/packages/core/scripts/sentry_utils.rb
index 43a778c019..90c535556a 100644
--- a/packages/core/scripts/sentry_utils.rb
+++ b/packages/core/scripts/sentry_utils.rb
@@ -165,3 +165,52 @@ def ensure_sentry_xcframework(version, product = 'Sentry')
   target_dir
 end
 
+# Stage the cached xcframework behind a machine-independent `$(PODS_ROOT)`
+# reference.
+#
+# Everything assigned to `pod_target_xcconfig`/`user_target_xcconfig` is part
+# of the evaluated spec, and CocoaPods derives the pod's `SPEC CHECKSUM` in
+# `Podfile.lock` from exactly that evaluated spec. Pointing
+# `FRAMEWORK_SEARCH_PATHS` at the per-user cache directory
+# (`~/Library/Caches/…`) therefore leaked `$HOME` into the checksum: two
+# machines installing the same SDK version produced different `RNSentry`
+# checksums and `Podfile.lock` churned on every `pod install` (#6467).
+#
+# Instead, symlink `Pods/sentry-xcframeworks/<version>/<product>.xcframework`
+# to the cached bundle and reference it as
+# `$(PODS_ROOT)/sentry-xcframeworks/…` — a string that is identical on every
+# machine (including ones overriding `SENTRY_XCFRAMEWORK_CACHE_DIR`).
+# `$(PODS_ROOT)` is defined by CocoaPods in both the per-pod and the
+# user/aggregate xcconfigs, unlike `$(PODS_TARGET_SRCROOT)`, and the link
+# lives inside `Pods/` so no Podfile-layout detection is needed.
+#
+# Returns the `$(PODS_ROOT)`-based path, or nil when the symlink cannot be
+# created — callers should fall back to the absolute cache path (previous
+# behaviour, functional but with a machine-specific checksum).
+def stage_sentry_xcframework_in_pods(xcframework_dir, version, product = 'Sentry')
+  pods_root = if defined?(Pod::Config) && Pod::Config.instance.respond_to?(:sandbox_root)
+                Pod::Config.instance.sandbox_root.to_s
+              else
+                File.join(Dir.pwd, 'Pods')
+              end
+  staging_dir = File.join(pods_root, 'sentry-xcframeworks', version)
+  link_path = File.join(staging_dir, "#{product}.xcframework")
+
+  FileUtils.mkdir_p(staging_dir)
+  # Recreate the link when it's missing or points at a stale location
+  # (e.g. `SENTRY_XCFRAMEWORK_CACHE_DIR` changed between installs).
+  unless File.symlink?(link_path) && File.readlink(link_path) == xcframework_dir
+    FileUtils.rm_rf(link_path)
+    File.symlink(xcframework_dir, link_path)
+  end
+
+  "$(PODS_ROOT)/sentry-xcframeworks/#{version}/#{product}.xcframework"
+rescue StandardError, NotImplementedError => e
+  if defined?(Pod::UI)
+    Pod::UI.warn "[Sentry] Could not link the #{product} xcframework into Pods/ " \
+                 "(#{e.class}: #{e.message}). Falling back to the absolute cache path; " \
+                 "the RNSentry checksum in Podfile.lock will be machine-specific."
+  end
+  nil
+end
+