Workshop Website
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Updated
Mar 24, 2025 - R
Workshop Website
Gene Set Integrative Analysis of Multi-Omics
A short research into commonalities of Parkinson's and Type 2 diabetes using network propagation on a PPI
mND uses multi-layer Network Diffusion to find gene networks that contain high scoring genes. It considers two or more "layers" of genome-wide scores and an interactome.
I discuss and demonstrate the impact of seed nodes selection on information diffusion in a network. I then show how insights obtained by data mining on a network can be integrated with a LLM - like Claude - by building connectors using the Model Context Protocol (MCP) architecture so that users can ask network related questions in natural language.
Network diffusion algorithms in R.
Phosphoproteomic analysis of ALMS1 and BBS1 gene knockout fibroblasts for the study of the TGF-B pathway.
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